Gains charges through soul, black, and white hearts. After 6 full hearts are absorbed, it will spawn varying amounts of consumables and items from the Angel room pool.
One time use, 12 charges to use
The Bible
Upon activation, Isaac gains Flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but will kill Isaac when activated while fighting Satan.
6
Blank Card
Has the same effect as the card or rune currently held by Isaac.
4
The Boomerang
Throws a short-range boomerang which does a bit of damage and has a high chance to stun the enemy for 2 seconds. Can also be used to grab pickups.
4 seconds
The Candle
Throws out a blue flame that can pass over gaps (but not through rocks). The flame damages anything in its path.
4 seconds
Converter
When used, converts two soul hearts into a heart container.
Throws an eraser which instantly kills the first enemy it hits, also killing all other copies in the room. If it hits a non-boss, prevents them from spawning for the rest of the run.
One time use
The Jar
When at full health, up to 4 extra hearts can be stored in the jar.
Gives Isaac a random Pill, and will cause him to drop any held Q-slot item (If any). The player will only receive six different pill types in one playthrough.
Chance upon entering a room to slow down or speed up every enemy and their attacks. The chance to slow enemies is quite higher than the chance to speed them up.
Champion Belt
Increases damage, but also increases the chance of Champion enemies appearing.
The Compass
Reveals all special rooms (except secret rooms of any kind).
Fanny Pack
Has a chance to drop a random pickup when Isaac takes damage.
Habit
When Isaac is hit, 1 point of an item's charge is filled.
Hive Mind
Increases the size of Blue Spiders and Blue Flies and doubles the amount of damage they deal.
Gives one extra pickup (1+1 Free version) of Red Hearts, pennies, bombs and Keys. Does not work with blue, black and half red hearts, nickels and dimes.
The Ladder
Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkable sections.
Little Baggy
Isaac can hold 2 pills at once and all cards are replaced by pills.
Mom's Key
Spawns 2 keys. Generates additional pickups from chests.
Mom's Coin Purse
Spawns 4 random Pills around Isaac.
Mom's Purse
Allows Isaac to hold 1 additional trinket.
PHD
Converts all bad pills into good pills, spawns one pill pickup and restores health. Identifies all pills upon pickup.
Piggy Bank
Gives 3 pennies on pick-up. Every time Isaac is damaged, he will drop one additional penny.