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For changes to Rebirth items, see Changes.

Items are an integral part of game-play in The Binding of Isaac: Rebirth. They modify Isaac's Attributes, grant or modify Tear Effects, and much more. Antibirth adds over 90 new items.

Active Items[edit | edit source]

Name Icon Description Recharge
Alabaster BoxAlabaster Box Icon.pngGains charges through soul, black, and white hearts. After 6 full hearts are absorbed, it will spawn varying amounts of consumables and items from the Angel room pool.One time use, 12 charges to use
Black MushroomBlack Mushroom Icon.pngReduces tear delay but distorts the screen for a length of time. Can be used multiple times to stack the effect. Tear delay is reset on changing rooms; however, the distortion persists.1 second
Book Of DespairBook Of Despair Icon.pngIncreases tears for the current room.3
Book Of VirtuesBook Of Virtues Icon.pngSummons a temporary flame familiar that fires spectral tears, deal contact damage to enemies and blocks enemy shots. Flames are consumed after taking a certain amount of damage or touching enemies. A maximum of 16 flames can be active at once: one inner ring of eight and an outer ring of eight.2
Bowl of TearsBowl of Tears Icon.pngFires a cluster of tears. Each tear shot by Isaac increases item charge by one.6
D12D12 Antibirth Icon.pngRe-rolls all rocks in the current room into other random objects, such as bomb rocks, metal blocks, TNT, or poop.3
DamoclesDamocles Icon.pngSpawns a sword above Isaac's head. After taking damage at least once, the sword can fall at any time, instantly killing him. While he is alive, he receives bonus items from all sources.One time use
EraserEraser Icon.pngPrevents an enemy from appearing for the rest of the run.One time use
Eternal D6Eternal D6 Icon.pngRerolls items with chance of disappearing.3
Fortune CookieFortune Cookie Icon.pngDisplays a random fortune, and has a chance to drop a soul heart, card, rune or trinket.2
Free LemonadeFree Lemonade Icon.pngCreates a large puddle of lemonade that damages enemies.4
Magic SkinMagic Skin Icon.pngGenerates one item from the current room's item pool and gives Isaac a broken heart, which permanently decreases the maximum health limit.6
Meat CleaverMeat Cleaver Icon.pngSplits all enemies in a room into 2 smaller versions of themselves with lower health.2
Mega MushMega Mush Icon.pngGigantifies Isaac for a short duration.12
Mom's BraceletMom's Bracelet Icon.pngAllows the player to grab obstacles and throw them, damaging enemies.1 second
R KeyR Key Icon.pngUpon use, restarts the game to the first floor, keeping all previously collected items. Game timer does not restart. Allows angels rooms to be found even if the previous run included devil deals.One time use
Red KeyRed Key Icon.pngCreates a red colored room on the map near Isaac's current position. The room can be anything from a regular encounter room to a Devil Room.3
The ScooperThe Scooper Icon.pngSummons a Peep familiar for the current room, which leaves a trail of red creep.3
Sharp KeySharp Key Icon.pngAllows Isaac to consume keys and fire them at enemies. Adds 5 keys.0
StitchesStitches Icon.pngSpawns a familiar that flies diagonally across the room, switching direction upon hitting walls. Activating the item swaps the positions of Isaac and Stitches.3 seconds
SulfurSulfur Icon.pngGrants Brimstone for the current room.3
Voodoo PinVoodoo Pin Icon.pngHurts Isaac without actually damaging him, activating any items that would trigger upon taking damage.2
Yuck HeartYuck Heart Icon.pngUpon use, grants a rotten heart.4

Passive Collectibles[edit | edit source]

Name Icon Description
120 Volt120 Volt Icon.pngWhenever an enemy is shot, it will zap other enemies near them, dealing damage.
2Spooky2Spooky Icon.pngEnemies near Isaac will be inflicted with Fear, causing them to flee from him.
A Bar Of SoapA Bar Of Soap Icon.pngIncreases tears and shot speed.
Act Of ContritionAct Of Contrition Icon.pngGrants an Immortal Heart and increases tears.
AkeldamaAkeldama Icon.pngWhenever Isaac fires a shot, a bloody tear will spawn behind him. Multiple tears will form a trail of tears that drags behind Isaac as he moves, bursting and dealing damage upon contact with enemies. Multiple trails can be formed.
Almond MilkAlmond Milk Icon.pngUpgrades fire rate immensely but significantly decreases damage, and tears are given random worm effects.
Battery PackBattery Pack Icon.pngRecharges Isaac's currently held active item and drops 2-4 batteries.
Bird CageBird Cage Icon.pngUpon taking damage the first time in a room, the familiar leaps from Isaac's head, targets an enemy, and lands on them, dealing damage and releasing a rock wave. For the rest of the room, the familiar targets and attacks enemies similar to Dead Bird.
Bird's EyeBird's Eye Icon.pngAdds a chance to spit a large fire whenever Isaac fires a tear.
BirthrightBirthright Icon.pngGrants different effects depending on which character you're playing as.
Blood BombsBlood Bombs Icon.pngGrants 1 heart container. Bombs create puddles of damaging red creep upon exploding. If Isaac has no bombs, bomb can be placed at the cost of half a heart.
Blood OathBlood Oath Icon.pngStabs Isaac at the beginning of each floor, draining all but half a heart of his heart containers. Increases damage and speed.
Boiled BabyBoiled Baby Icon.pngGrants a familiar similar to a Boil that periodically fires bursts of bullets.
Booster PackBooster Pack Icon.pngSpawns 3 tarot cards.
Bot FlyBot Fly Icon.pngGrants a familiar that fires shielded tears at incoming bullets.
Consolation PrizeConsolation Prize Icon.pngRaises Isaac's current lowest stat. Can also drop a consumable for whichever Isaac has the least of.
Dirty MindDirty Mind Icon.pngDestroying poop spawns friendly Dips that follow the player and damage enemies. Destroying different types of poop spawns different Dips with special effects.
Donkey JawboneDonkey Jawbone Icon.pngWhenever Isaac takes damage, a spin attack will damage enemies around him.
Enigma BombsEnigma Bombs Icon.pngGrants 5 bombs. Bombs explode with a random bomb effect.
Evil CharmEvil Charm Icon.pngGrants +3 luck.
Eye DropsEye Drops Icon.pngIncreases tears. Tears fire at different rates from each of Isaac's eyes.
Eye Of The OccultEye Of The Occult Icon.pngIncreases damage. Tears can be controlled mid-flight using the fire keys.
Eye SoreEye Sore Icon.pngFrequently fire tears in random directions in addition to regular tears. Can fire up to three extra tears.
Freezer BabyFreezer Baby Icon.pngGrants a familiar that fires shots that freeze enemies. Frozen enemies explode into ice shards when touched.
Immaculate HeartImmaculate Heart Icon.pngFire orbiting tears along with normal tears.
The IntruderThe Intruder Icon.pngIsaac will now fire four slowing tears in addition to normal tears. Upon taking damage multiple times in one room, Isaac's head will pop, spawning friendly spiders and a familiar that leaps at enemies.
It HurtsIt Hurts Icon.pngTaking damage causes Isaac to release a ring of bloody tears and increases fire rate for current room.
Jacob's LadderJacob's Ladder Icon.pngGenerates a ladder in the starting room next floors, which leads to an Angel Room.
Knife Piece 1Knife Piece 1 Icon.pngHas no effect on its own. Picking up all three pieces grants a knife familiar that damages enemies and grants access to the Corpse.
Knife Piece 2Knife Piece 2 Icon.pngHas no effect on its own. Picking up all three pieces grants a knife familiar that damages enemies and grants access to the Corpse.
Knife Piece 3Knife Piece 3 Icon.pngHas no effect on its own. Picking up all three pieces grants a knife familiar that damages enemies and grants access to the Corpse.
Knockout DropsKnockout Drops Icon.pngAdds a chance to fire fist tears, which have massive knockback and briefly stun enemies.
Lil' DumpyLil' Dumpy Icon.pngGrants a familiar that loosely follows the player. Farts when hit by enemy attacks.
LodestoneLodestone Icon.pngAdds a chance to fire magnetizing tears. Magnetized enemies attract other enemies, Isaac's tears, and enemy shots including their own.
Lost SoulLost Soul Icon.pngSpawns a familiar version of The Lost that follows Isaac. Upon being hit, it instantly dies, regenerating on the next floor. If it survives an entire floor, it grants a random reward.
LunaLuna Icon.pngAdds one extra Secret Room and one Super Secret Room on each floor.
MarsMars Icon.pngGain the ability to charge by double-tapping in a direction. Isaac is invincible during the charge and deals significant damage. Can be used multiple times per room with a short recharge time.
Member CardMember Card Icon.pngOpens a trapdoor with a ladder in every shop. The trapdoor leads to a special shop room, which sells multiple items or pickups for random prices. Sold collectibles don't have to be from the Shop pool.
MenorahMenorah Icon.pngSpawns a menorah familiar that grants an extra tear per shot for each candle lit. The menorah starts with one candle lit, and each time Isaac is hit, another candle is lit, up to a maximum of 7 tears per shot. Being hit an additional time will release blue flames that damage enemies and reset the menorah.
MercuriusMercurius Icon.pngDoors stay open after entering a room, even with enemies in it, allowing Isaac to leave any time. Increases speed.
MonstranceMonstrance Icon.pngIsaac emits an aura that damages nearby enemies.
MucormycosisMucormycosis Icon.pngUpon enemies' death, they release a cloud of gas that damages and poisons other enemies.
Oculus RiftOculus Rift Icon.pngAdds a chance to fire tears that summon rifts wherever they land. Rifts attract enemies, enemy shots, Isaac's tears, and pickups. They also deal contact damage to enemies caught in them.
Orphan SocksOrphan Socks Icon.pngIsaac gains 2 spirit hearts and can walk on harmful floor effects.
Paschal CandlePaschal Candle Icon.pngIncreases tears for each room completed without taking damage. Resets on taking damage.
Playdoh CookiePlaydoh Cookie Icon.pngAdds random effects to tears.
PlutoPluto Icon.pngDecreases Isaac's size to the point where many tears will fly over Isaac. Increases tears and speed, and decreases range.
Psy FlyPsy Fly Icon.pngCatches enemy shots and flings them back at enemies as homing tears.
Red StewRed Stew Icon.pngRestores all red heart containers. Grants an enormous damage boost that wears off over time.
RevelationRevelation Icon.pngAdds 2 Immortal Hearts, grants flight, gives tears a Brain Worm-like homing effect, decreases range and increases shot speed.
Rock BottomRock Bottom Icon.pngAll stats down. Prevents stats from being lowered the rest of the run.
Rocket In A JarRocket In A Jar Icon.pngGrants 5 bombs. Bombs become rockets that fly in the direction Isaac is currently looking.
Rotten TomatoRotten Tomato Icon.pngTears have a chance to mark enemies. Marked enemies will be attacked by other enemies.
SaturnusSaturnus Icon.pngIsaac is surrounded by an aura which grants 7 orbiting tears when entering a new room and has a chance to absorb incoming enemy tears.
SausageSausage Icon.pngAll stats up.
SchoolbagSchoolbag Icon.pngGrants an extra active item slot.
SolSol Icon.pngActivates the Sun tarot card and fully recharges Isaac's active item upon defeating a boss. Reveals the location of the Boss room on the map.
Spirit SwordSpirit Sword Icon.pngReplaces Isaac's tears with a sword he can swing in front of him. Holding an attack button charges a spin attack. If Isaac is at full health, it also shoots a projectile when swung. Only one projectile can be active at once.
Stone BombsStone Bombs Icon.pngGrants 5 bombs. Bombs release rock waves in the cardinal directions, which can damage enemies, destroy obstacles, and damage Isaac.
TerraTerra Icon.pngIsaac's tears become rocks. The tears can also destroy rocks.
TinytomaTinytoma Icon.pngA large orbital that slowly orbits Isaac. Upon taking enough tear or contact damage, the orbital splits into two smaller ones that orbit opposite of each other. If the small orbitals take enough damage, they burst into a few blue spiders, and the large orbital respawns.
UranusUranus Icon.pngIsaac shoots ice tears.
VenusVenus Icon.pngEnemies near Isaac will be inflicted with Charm that wears off quickly after enemies move away from Isaac, causing enemies to attack each other.
Voodoo HeadVoodoo Head Icon.pngAdditional curse rooms can spawn each floor.

Sacdag.png Antibirth Sacdag.png

Boss Baby Plum.png Bosses MainPageChallenges.png Challenges MainPageChapters.png Chapters Character.png Characters Book of Virtues.png Items
Dumpling.png Monsters Bucket.png Objects Immortal Heart.png Pickups Blessed Penny Icon.png Trinkets MainPageAchievements.png Unlockables