The Binding of Isaac: Antibirth Wiki
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Rules Card Icon This article is about the changes of "The Binding of Isaac: Antibirth". For the main page, see Bosses.

Bosses are strong monsters found in boss rooms at the end of a floor. The boss at the end of the floor must be defeated to advance to the next floor. The boss for a particular floor is chosen from the pool of bosses for the environment of the floor. Upon defeat, most bosses will drop an item from the boss item pool.

Antibirth adds 16 new bosses and a few variants on existing bosses.

Normal Chapters

Chapter 1

Boss Baby Plum
Baby Plum

Chapter 3

Boss The Pile Boss Reap Creep
The Pile Reap Creep

Downpour

Boss Wormwood Boss Beelzeblub
Boss The Rainmaker
Boss The Haunt
Wormwood Beelzeblub The Rainmaker The Haunt

Mines

Boss Tuff Twins
Boss Great Gideon
Boss Hornfel
Boss Reap Creep
Tuff Twins Great Gideon Hornfel Reap Creep

Mausoleum

Floor 1

Boss The Heretic
Boss The Visage
Boss The Siren
Boss The Pile
The Heretic The Visage The Siren The Pile

Floor 2

Boss Mom
Mausoleum Mom

Corpse

Floor 1

Boss The Scourge
Boss Rotgut
Boss Chimera
The Scourge Rotgut Chimera

Floor 2

Boss The Witness
The Witness

Universal

These bosses have a chance of replacing a boss from an environment pool, including Antibirth floors.

Boss The Fallen
The Fallen


Bosses Boss Baby Plum
Rebirth Chapters Baby PlumReap CreepThe Pile
Downpour BeelzeblubThe RainmakerWormwood
Mines Great GideonHornfelTuff Twins
Mausoleum Mausoleum MomThe HereticThe SirenThe Visage
Corpse ChimeraRotgutThe ScourgeThe Witness

Sacdag Antibirth Sacdag

Boss Baby Plum Bosses MainPageChallenges Challenges MainPageChapters Chapters Character Characters Book of Virtues Items
Dumpling Monsters Bucket Objects Immortal Heart Pickups Blessed Penny Icon Trinkets MainPageAchievements Unlockables
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